Mother Herbs (P) Ltd

Uses : The root is used for a myriad of medicinal purposes. According to the ancient Sanskrit texts, coleus has been used as a medical herb to treat heart and lung diseases, intestinal spasms, insomnia and convulsions. It also lowers blood pressure, antispasmodic, dilates the blood vessels. It is found to be effective in skin conditions as eczema and psoriasis. Coleus is primarily indicated for cardiovascular diseases including hypertension, congestive heart failure and angina. It is also used for asthma, intestinal colic, uterine cramps as well as painful urination. Coleus can aid in digestive and malabsorption disorders through its ability to stimulate secretion of saliva, hydrochloric acid, pepsin, amalyase and pancreatic enzymes and increase nutrient absorption in the small intestine. It accelerates the breakdown of existing fat stores and promotes healthy cardiovascular function, lowers elevated blood pressure. Useful in treatment for eczema and other allergic condition. The oil finds useful applications in flavor and fragrance preparations as well as in aromatherapy.

Chemical Constituents and Components: Main chemical components are diterpenoids as diacetyl forskolin, allylroyleanone, barbatusin, plectrin, plectirinon A, acetoxycoleosol, coleol, coleonone, coleosol, deoxycoleonol, crocetin dialehyde a

Action :
Forskohlin : 1. It increases the amount of cyclic AMP (adenosine monophosphate) in cells by activating adenylate cyclase enzyme. 2. It inhibits mast cell degranulation and release of histamine and other allergic compounds. 3. It increases insulin secretion and thyroid functioning. 4. It inhibits platelet activation and degranulation. 5. It increases lipolysis of fats. 6. It shows transmembrane signaling which results in activation of other cellular enzymes. 7. It shows inhibition of pro-inflammatory substance known as platelet activating factor (PAF) 6.

Curing Diseases:1. It is helpful in hypertension and heart failure.
2. It is useful in eczema and psoriasis.
3. It is useful in asthma, colic and painful urination.
4. It is helpful in insomnia and convulsions.
5. It is helpful in digestion and malabsorption disorders.
6. It provides relaxation to arteries and smooth muscles.
7. It is also helpful to obese patients to lose body fat.

Research Information: Coleus forskolin root extract is useful in increasing body mass and decreases the body fat. (Ref. Badmaev, Valdimir and et.al., Diterpene Forskolin (Coleus forskoli, Benth.): A possible new compound for reduction of body weight by increasing lean body mass, 1999, Sabinsa Corporation, USA)